#176 - AMA #27: The importance of muscle mass, strength, and cardiorespiratory fitness for longevity
Sep 20, 2021
In this “Ask Me Anything” (AMA)
episode, Peter and Bob discuss the longevity benefits from greater
cardiorespiratory fitness (CRF) and greater muscle mass and
strength. Conversely, they dive deep into the literature showing a
rapid increase in morbidity and mortality risk as fitness levels
decline with age. They also try to tease out the relative
contributions of CRF, muscle mass, and strength. Additionally, they
discuss the impact of fasting on muscle mass, the potential
tradeoffs to consider, and finish by discussing why it’s critical
to maximize your fitness level.
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We
discuss:
- VO2 max and its association with
cardiorespiratory fitness [2:45];
- Changing mortality risk based on
VO2 max and cardiorespiratory fitness [7:45];
- The profound impact of improving
cardiorespiratory fitness [15:15];
- Muscle mass, function, and loss
with aging: how it’s defined, measured, and the cutoff points for
sarcopenia [25:00];
- Increasing mortality risk
associated with declining muscle mass and strength
[40:00];
- Muscle size vs. strength—which
has the bigger impact on mortality risk?
[58:00];
- Evaluating the cumulative impact
of cardiorespiratory fitness and muscular strength on mortality
risk when put together [1:03:30];
- Investigating the rising
incidence in deaths from falls, and what role Alzheimer’s disease
might play [1:09:00];
- The impact of fasting on muscle
mass and the potential tradeoffs to consider
[1:14:30];
- The critical importance of
working to maintain muscle mass and strength as we age [1:20:30];
and
- More.
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